Wissenschaftliche Arbeit

05/2020 Bräuer S, Günther R, Sterneckert J, Glaß H, Hermann A. Human Spinal Motor Neurons Are Particularly Vulnerable to Cerebrospinal Fluid of Amyotrophic Lateral Sclerosis Patients. Int J Mol Sci.

04/2020 Meyer T, Kettemann D, Maier A, Grehl T, Weyen U, Grosskreutz J, Steinbach J, Norden J, George A, Hermann A, Günther R, Petri S, Schreiber- Katz O, Dorst J, Ludolph AC, Walter B, Münch C, Spittel S. Symptomatic pharmacotherapy in ALS: data analysis from a platform-based medication management programme. JNNP.
 
03/2020 Hagenacker T*, Wurster CD*, Günther R*, Schreiber-Katz O, Osmanovic A, Petri S, Weiler M, Ziegler A, Kuttler J, Koch JC, Schneider I, Wunderlich G, Schloss N, Lehmann HC, Cordts I, Deschauer M, Lingor P, Kamm C, Stolte B, Pietruck L, Totzeck A, Kizina K, Mönninghoff C, von Velsen O, Ose C, Reichmann H, Forsting M, Pechmann A, Kirschner J, Ludolph AC, Hermann A, Kleinschnitz C. Lancet Neurol. 2020 Apr;19; * shared first authors.
 
03/2020 Mengmeng J*, Günther R*, Akgün K, Hermann A, Ziemsse T. Peripheral proinflammatory Th1/Th17 immune cell shift is linked to disease severity in amyotrophic lateral sclerosis. Scientific Reports. In press. * shared first author.
 
02/2020 Wurster CD, Günther R. Neue Therapien der spinalen MuskelatrophieNew treatments for spinal muscular atrophy. Der Nervenarzt.
 
12/2019 Hagenacker T, Hermann A, Kamm C, Walter MC, Weiler M, Günther R, Wurster CD, Kleinschnitz C. Spinal Muscular Atrophy - expert recommendations for the use of nusinersen in adult patients]. Fortschr Neurol Psychiatr.
 
11/2019 Wurster CD, Koch JC, Cordts I, Dreyhaupt J, Otto M, Uzelac Z, Witzel S, Winter B, Kocak B, Schocke M, Weydt P, Wollinsky K, Ludolph AC, Deschauer M, Lingor P, Tumani H, Hermann A, Günther R. Routine Cerebrospinal Fluid (CSF) Parameters in Patients With Spinal Muscular Atrophy (SMA) Treated With Nusinersen. Front Neurol.
 
11/2019 Günther R, Wurster CD, Cordts I, Koch JC, Kamm C, Petzold D, Aust E, Deschauer M, Lingor P, Ludolph AC, Hermann A. Patient-Reported Prevalence of Non-motor Symptoms Is Low in Adult Patients Suffering From 5q Spinal Muscular Atrophy. Front Neurol.
 
11/2019 Naumann M, Peikert K, Günther R, van der Kooi AJ, Aronica E, Hübers A, Danel V, Corcia P, Pan-Montojo F, Cirak S, Haliloglu G, Ludolph AC, Goswami A, Andersen PM, Prudlo J, Wegner F, Van Damme P, Weishaupt JH, Hermann A. Phenotypes and malignancy risk of different FUS mutations in genetic amyotrophic lateral sclerosis. Ann Clin Transl Neurol.
 
09/2019 Wurster CD*, Steinacker P*, Günther R, Koch JC, Lingor P, Uzelac Z, Witzel S, Wollinsky K, Winter B, Osmanovic A, Schreiber-Katz O, Al Shweiki R, Ludolph AC, Petri S, Hermann A, Otto M. Neurofilament light chain in serum of adolescent and adult SMA patients under treatment with nusinersen. Journal of Neurology 09/2019
 
08/2019 Hagenacker T, Hermann A, Kamm C, Walter MC, Weiler M, Günther R, Wurster CD, Kleinschnitz C. Spinale Muskelatrophie - Expertenempfehlungen zur Behandlung von erwachsenen Patienten mit Nusinersen / Spinal Muscular Atrophy – expert recommendations for the use of nusinersen in adult patients. Fortschritte der Neurologie – Psychiatrie (in press)
 
04/2019 Wurster C, Günther R, Steinacker P, Dreyhaupt J, Wollinsky K, Uzelac Z, Witzel S, Kocak T, Winter B, Koch JC, Lingor P, Petri S, Ludolph AC, Hermann A, Otto M. Neurochemical markers in CSF of adolescent and adult SMA patients under treatment with nusinersen. Ther Adv Neurol Disord
 
04/2019 Peikert K, Naumann M, Günther R, Wegner F, Hermann A. Off-Label Treatment of 4 Amyotrophic Lateral Sclerosis Patients With 4-Aminopyridine. J Clin Pharmacol
 
04/2019 Lingor P, Weber M, Camu W, Friede T, Hilgers R, Leha A, Neuwirth C, Günther R, Benatar M, Kuzma-Kozakiewicz M, Bidner H, Blankenstein C, Frontini R, Ludolph A, Koch JC and the ROCK-ALS Investigators ROCK-ALS: Protocol for a Randomized, Placebo-Controlled, Double-Blind Phase IIa Trial of Safety, Tolerability and Efficacy of the Rho Kinase (ROCK) Inhibitor Fasudil in Amyotrophic Lateral Sclerosis. Front Neurol
 
01/2019 Winter B, Günther R, Ludolph AC, Hermann A, Otto M, Wurster CD: Neurofilaments and tau in CSF in an infant with SMA type 1 treated with nusinersen. JNNP
 
01/2019 Walter MC, Dräger B, Günther R, Hermann A, Hagenacker T, Kleinschnitz C, Löscher  W, Meyer T, Schrank B, Schwersenz I, Wurster CD, Ludolph AC, Kirschner J (2019): Therapieevaluation bei Patienten mit 5q-assoziierter Spinaler Muskelatrophie. Erfahrungen aus der klinischen Praxis. Der Nervenarzt
 
11/2018 Günther R, Neuwirth C, Koch JC, Lingor P, Braun N, Untucht R, Petzold D, Weber M, and Hermann A (2018): Motor Unit Number Index (MUNIX) of hand muscles is a disease biomarker for adult spinal muscular atrophy. Clin Neurophysiol
 
02/2018 Günther R, Schrempf W, Hähner A, Hummel T, Wolz M, Storch A, Hermann A (2018): Impairment in respiratory function contributes to olfactory impairment in Amyotrophic Lateral Sclerosis. Front. Neurol.
 
01/2018 Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, Naujock M, Günther R, …, Hermann A (2018): Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. Nat Commun.
         
01/2017 Günther R, Balck A, Koch JC, Nientiedt T, Sereda M, Bähr M, Lingor P, Tönges L (2017): Rho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis-Symptomatic Treatment Potential after Disease Onset. Front Pharmacol.
 
07/2016 Günther R, Richter N, Sauerbier A, Chaudhuri KR, Martinez-Martin P, Storch A, Hermann A (2016): Non-Motor Symptoms in Patients Suffering from Motor Neuron Diseases. Front Neurol.     
 
10/2014 Günther R, Saal KA, Suhr M, Scheer D, Koch JC, Bähr M, Lingor P, Tönges L (2014): The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice. Front Neurosci.
 
02/2014 Tönges L, Günther R, Suhr M, Jansen J, Balck A, Saal K, Barski E, Nientied T, Götz AA, Koch J et al. (2014): Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis. Glia.
 
03/2012 Günther R, Suhr M, Koch JC, Bähr M, Lingor P, Tönges L (2012): Clinical testing and spinal cord removal in a mouse model for amyotrophic lateral sclerosis (ALS). J Vis Exp.