Literatur

Literatur (Auswahl)
 
Klinik:
 
A. C. Ludolph: Amyotrophe Lateralsklerose. In: P. Berlit (Hrsg.): Klinische Neurologie. 2. Auflage. Springer Verlag, Heidelberg 2006. ISBN 978-3-540-01982-4. S.541–550.
 
K. Kollewe, P. M. Andersen, G. D. Borasio et al: Klinische Leitlinien zur Behandlung der Amyotrophen Lateralsklerose. In: Nervenheilkunde. (2008) 27 4:302–316.
 
Rothstein JD. Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann Neurol. 2009 Jan;65 Suppl 1:S3-9.
 
Davies, Z. and M. R. Turner "Public awareness of motor neuron disease." Amyotroph Lateral Scler 11(5): 490-1.
 
Genetik:
 
Dion PA, Daoud H, Rouleau GA. Genetics of motor neuron disorders: new insights into pathogenic mechanisms. Nat Rev Genet. 2009 Nov;10(11):769-82.
 
Millecamps, S., F. Salachas, et al. "SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype-phenotype correlations." J Med Genet 47(8): 554-60.
 
H.X. Deng, H. Zhai, E.H. Bigio et al., FUS-Immunoreactive Inclusions Are a
Common Feature in Sporadic and Non-SOD1 Familial Amyotrophic Lateral Sclerosis. Ann Neurol 2010;67:739–748.
 
I.R.A. Mackenzie, E. H. Bigio, P.G. Ince et al., Pathological TDP-43 Distinguishes Sporadic
Amyotrophic Lateral Sclerosis from Amyotrophic Lateral Sclerosis with SOD1 Mutations. Ann Neurol 2007;61:427–434.
 
Grundlagenwissenschaft:
 
Boillee, S., K. Yamanaka, et al. (2006). "Onset and progression in inherited ALS determined by motor neurons and microglia." Science 312(5778): 1389-92.
 
Di Giorgio, F. P., G. L. Boulting, et al. (2008). "Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation." Cell Stem Cell 3(6): 637-48.
 
Dimos, J. T., K. T. Rodolfa, et al. (2008). "Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons." Science 321(5893): 1218-21.
 
Gurney, M. E., T. J. Fleck, et al. (1998). "Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis." Neurology 50(1): 62-6.
 
Ludolph, A. C., C. Bendotti, et al. "Guidelines for preclinical animal research in ALS/MND: A consensus meeting." Amyotroph Lateral Scler 11(1-2): 38-45.
 
H.-J. Habisch, M. Janowski, D. Binder, M. Kuzma-Kozakiewicz, A. Widmann, A. Habich, B. Schwalenstoecker, A. Hermann, R. Brenner, B. Lukomska, K. Domanska-Janik, A. C. Ludolph, A. Storch. Intrathecal application of neuroectodermally converted stem cells into a mouse model of ALS: limited intraparenchymal migration and survival narrows therapeutic effects. J Neural Transm (2007) 114: 1395–1406